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NCT07894016
Comparison of Amoxicillin, Clindamycin and Azithromycin Single Doses Antibiotic Prophylaxis in Patient Undergoing Lower Third Molar Extraction
Conditions: Wisdom Tooth Removal, Antibiotic Prophylaxis, Single Dose
Sex: All
Ages: 18 Years – N/A
Healthy volunteers: No
Phase: PHASE4
Enrollment: 105
Sponsor: Dow University of Health Sciences
Location: Dr. Ishrat-ul-Ebad Khan Institute of Oral Health Sciences Karachi Sindh
Summary
The goal of this clinical trial is to learn which drug amongst Amoxicillin, Clindamycin and Azithromycin single dose works better in reducing post-surgical complications in Participants getting lower wisdom teeth pulled. The main question it aims to answer is:
• Which single dose drug lowers the post-surgical complications in participants of this study? Researcher will compare three single dose drugs (the administration of the complete amount of an antibiotic medication in one single administration to cure or prevent an infection).
Participants will:
* Take provided drug one hour before the treatment
* Visit the OPD for Reading measurements same day before the surgery, same day after the surgery and third day after the surgery.
Eligibility Criteria
Inclusion Criteria:
* Individuals with no history antibiotics for past 1 month
* No active infection going
* No allergies to any antibiotics, analgesics, local anesthetic
* Cases of low to medium difficulty
* Age bracket from 18 years or older
Exclusion Criteria:
* Pregnant women
* Lactating mothers
* People who have any soft tissue healing disorder
* Patient undergone radiotherapy
* Patient having kidney or liver disease
Source: ClinicalTrials.gov (NCT07894016). StuddyBuddy aggregates publicly available trial information.