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NCT07888829
G-CSF In Neonatal Sepsis With Neutropenia
Conditions: Neonatal Sepsis, Neutropenia
Sex: All
Ages: 0 Days – 28 Days
Healthy volunteers: No
Phase: NA
Enrollment: 52
Sponsor: University of Health Sciences Lahore
Location: Children's hospital University of Child Health Sciences Lahore Lahore Punjab Province
Summary
This study will evaluate whether adding G-CSF to standard treatment improves outcomes in newborns (0-28 days) with sepsis and neutropenia. It will compare survival, recovery of neutrophil counts, hospital stay, infections, and adverse effects between babies receiving G-CSF and standard treatment alone.
Eligibility Criteria
Inclusion Criteria:
* Neonates aged 0-28 days admitted to the Department of Neonatology/The Children's Hospital Lahore.
* Neonates diagnosed with sepsis according to the study's operational definition.
* Absolute neutrophil count (ANC) less than 1500/µL.
Exclusion Criteria:
* Neonates with congenital anomalies.
* Neonates with birth asphyxia.
* Neonates with primary immunodeficiency.
* Neonates already receiving treatment with colony-stimulating factor.
* Neonates already receiving any other adjuvant therapy.
Source: ClinicalTrials.gov (NCT07888829). StuddyBuddy aggregates publicly available trial information.
