Manual Acupuncture for Intradialytic Nausea and Vomiting in Patients Undergoing Hemodialysis: A Randomized Controlled Trial

This study aims to evaluate the immediate effects of acupuncture therapy at three specific acupuncture points (PC6, ST36, and KI3) on intradialysis nausea and vomiting in patients with chronic kidney disease undergoing regular hemodialysis. The outcome will be assessed using the Rhodes Index of Nausea, Vomiting, and Retching (RINVR) score one hour during the treatment and two hours after completion of hemodialysis.

Inclusion Criteria: * Patients with chronic kidney disease (CKD) who experience intradialytic nausea and vomiting, undergo routine hemodialysis twice weekly for at least 6 months, and are hemodynamically stable. * Subjects aged 18-59 years. * Subjects who have not received acupuncture therapy within at least one month prior to the study. * Subjects who are willing to participate in the study according to the scheduled protocol until completion and who have signed the informed consent form. Exclusion Criteria: * Subjects with malignancies or infected wounds at the acupuncture point sites intended for intervention. * Subjects with primary skin diseases, such as allergic dermatitis, irritant contact dermatitis, neurodermatitis, and psoriasis. * Subjects with a history of hypersensitivity reactions to previous acupuncture therapy, including stainless steel allergy, atopy, keloid formation, or other hypersensitivity reactions.