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NCT07879755
An Extension Trial of GW 906 in Participants With Essential Hypertension
Conditions: Hypertension
Sex: All
Ages: 18 Years – N/A
Healthy volunteers: No
Phase: NA
Enrollment: 1500
Sponsor: Shenzhen Salubris Pharmaceuticals Co., Ltd.
Location: Shanghai Jiao Tong University School of Medicine, Ruijin Hospital Shanghai Shanghai Municipality
Summary
This clinical study was designed to assess the safety and efficacy of long-term dosing of GW906
Eligibility Criteria
Inclusion Criteria:
* Completed study treatment and the study in accordance with the protocol for GW906 injection.
* Willing to participate in the study and provide written informed consent.
Exclusion Criteria:
* Secondary hypertension.
* Orthostatic hypotension accompanied by hypotension-related symptoms was observed in a prior study of GW906 injection.
* Alanine aminotransferase (ALT) or aspartate aminotransferase (AST) \>2.5× upper limit of normal (ULN); Total bilirubin \> 1.5 × ULN; International normalized ratio (INR) \> 2.0; Serum potassium \> 5.0 mmol/L or \< 3.5 mmol/L; eGFR≤30 mL/min/1.73m\^2.
* History of any cardiovascular event within 6 months.
* Patients with active malignancy or a history of malignancy.
Source: ClinicalTrials.gov (NCT07879755). StuddyBuddy aggregates publicly available trial information.