Sevoflurane Versus Propofol Anesthesia in Intracardiac Echocardiography-Guided Atrial Fibrillation Ablation

This prospective, randomized, single-center study will compare sevoflurane inhalational anesthesia with propofol intravenous anesthesia in patients undergoing intracardiac echocardiography-guided radiofrequency catheter ablation for atrial fibrillation. Eligible participants will be randomly assigned to one of two general anesthesia groups. In the sevoflurane group, anesthesia will be maintained with sevoflurane, while in the propofol group, anesthesia will be maintained with propofol administered using target-controlled infusion. In both groups, anesthesia depth will be adjusted to maintain a Bispectral Index value between 40 and 60. The study will evaluate acute procedural success and atrial arrhythmia recurrence at 6 months. Additional outcomes will include mapping time, ablation time, total procedure time, hemodynamic instability, recovery score, and procedural complications.

Inclusion Criteria: * Patients diagnosed with atrial fibrillation who are scheduled to undergo elective intracardiac echocardiography-guided radiofrequency catheter ablation. * Patients aged 18 to 64 years who provide informed consent to participate in the study. * Patients aged 65 to 90 years with a Mini-Mental State Examination score of 24 or higher who provide informed consent to participate in the study. Exclusion Criteria: * Known allergy to propofol. * Known allergy to sevoflurane. * Left ventricular ejection fraction below 35%. * Previous catheter ablation. * Emergency ablation procedure. * Refusal to provide informed consent for study participation. * Patients aged 65 to 90 years with a Mini-Mental State Examination score below 24.