Effectiveness of Sensorimotor Proprioceptive Stimulation Combined With Conventional Physical Therapy on Symptoms, Sensory Function, Proprioception, and Hand Function in Patients With Mild-to-Moderate Carpal Tunnel Syndrome

This randomized controlled trial will evaluate whether adding sensorimotor proprioceptive stimulation to conventional physiotherapy improves symptoms and hand function in patients with mild-to-moderate carpal tunnel syndrome. The primary outcome is change in the Boston Symptom Severity Scale, while secondary outcomes include functional status, pain, paresthesia, nerve conduction, median-nerve morphology, proprioception, and hand strength.

Inclusion Criteria: * Are adults aged 30-50 years. * Have clinically diagnosed mild-to-moderate carpal tunnel syndrome. * Report pain, numbness, tingling, or nocturnal symptoms in the median-nerve distribution. * Have symptoms lasting at least 4 weeks. * Have electrodiagnostic findings consistent with mild-to-moderate median-nerve compression at the wrist. * Can understand and follow study instructions. * Can attend treatment and assessment sessions. * Provide written informed consent. Exclusion Criteria: * Severe carpal tunnel syndrome requiring immediate surgery. * Previous carpal tunnel release or wrist surgery. Cervical radiculopathy, brachial plexopathy, or another peripheral neuropathy. * Diabetes, rheumatoid arthritis, thyroid disease, or other systemic conditions affecting nerve function, unless medically stable and permitted by the protocol. * Wrist fracture, arthritis, tendon injury, or other upper-limb musculoskeletal disorders. * Pregnancy.