Preterm Parturation Study

Conditions: Preterm Parturation, Preterm Premature Rupture of Membranes (PPROM)

Sex: Female

Ages: 18 Years – N/A

Healthy volunteers: No

Enrollment: 300

Sponsor: Medical University of Graz

Location: Medical University of Graz Department of Obstetrics and Gynecology Graz Styria

Summary

In this study (study group) non-invasively measured fetal parameters in pregnant patients with preterm premature rupture of membranes (PPROM) or preterm parturation (cervical dilation before 37+0 weeks of gestation) will be examined for their association with short-term neonatal outcomes as well as with specific hematological and immunological parameters of the newborn. The control group includes pregnant women who are due to give birth around their due date (between 37+0 and 41+3 weeks of gestation, without premature rupture of membranes or preterm parturation).

Eligibility Criteria

Inclusion Criteria: * Preterm rupture of membranes between 20+0 and 36+6 weeks of gestation * Expectant management with the goal of providing the highest level of neonatal care * Maternal age 18 years or older * Singleton pregnancy Exclusion Criteria: * Palliative care plan (neonatal "comfort care") * Maternal age under 18 * Multiple pregnancy * Significant fetal genetic abnormalities or malformations * Underlying maternal (auto)immune conditions * Participation in other clinical trials

Interested in this study? View the official listing for contact and enrollment details.

View on ClinicalTrials.gov

Source: ClinicalTrials.gov (NCT07869160). StuddyBuddy aggregates publicly available trial information.