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NCT07857356
Remifentanil Versus Remifentanil-Lidocaine for Tracheal Extubation After Thyroidectomy
Conditions: Tracheal Extubation, Cough
Sex: All
Ages: 18 Years – 65 Years
Healthy volunteers: No
Phase: PHASE4
Enrollment: 60
Sponsor: Pamukkale University
Location: Pamukkale University Hospitals Denizli
Summary
This randomized, double-blind clinical trial will compare the effects of remifentanil alone and remifentanil combined with intravenous lidocaine on the quality of tracheal extubation in adult patients undergoing elective thyroidectomy under general anesthesia.
A total of 60 patients will be randomly assigned to two groups. Both groups will receive remifentanil during emergence from anesthesia, while one group will additionally receive intravenous lidocaine before extubation.
The primary outcome will be the incidence of coughing during tracheal extubation. Secondary outcomes will include cough severity, hemodynamic responses, oxygen saturation, airway-related adverse events, postoperative sore throat, hoarseness, postoperative nausea and vomiting, sedation level, and recovery and extubation times.
Eligibility Criteria
Inclusion Criteria:
* Age 18 to 65 years American Society of Anesthesiologists (ASA) physical status I or II Scheduled for elective thyroidectomy under general anesthesia Body mass index (BMI) \
Source: ClinicalTrials.gov (NCT07857356). StuddyBuddy aggregates publicly available trial information.