Retinal and Choroidal Changes in Periodontal Disease

Conditions: Periodontal Diseases, Periodontal Diseases Inflammation, Retinal Thickening

Sex: All

Ages: 20 Years – 54 Years

Healthy volunteers: Yes

Enrollment: 80

Sponsor: Zeliha Başak Çakır Erdil

Location: Faculty of Dentistry, Adıyaman University Adıyaman Adıyaman Province

Summary

Advanced PeriodontitisIn this cross-sectional study, the relationship between periodontal disease severity and retinal and choroidal structural changes was evaluated using SD-OCT. Data from a total of 80 participants were examined. It was found that choroidal thickness increased and ganglion cell layer thickness decreased as periodontal disease severity increased, while no significant relationship was found in RNFL and IPL thicknesses. The findings support a possible association between periodontal disease and ocular structural changes.

Eligibility Criteria

Inclusion Criteria: Systemically healthy adults. Non-smokers (no current or previous tobacco use). Participants who underwent optical coherence tomography (OCT) imaging. Participants who provided written informed consent and agreed to participate in the study. Exclusion Criteria: Presence of any systemic disease. Current or former smokers. Participants with incomplete clinical or OCT data. Individuals who did not provide written informed consent. \-

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View on ClinicalTrials.gov

Source: ClinicalTrials.gov (NCT07856901). StuddyBuddy aggregates publicly available trial information.