Cryoneurolysis Versus Bipolar Radiofrequency Ablation of Genicular Nerves for Pain Relief in Symptomatic Knee Osteoarthritis

Conditions: Cryoneurolysis, Bipolar Radiofrequency Ablation, Genicular Nerves, Pain Relief, Symptomatic, Knee Osteoarthritis

Sex: All

Ages: 40 Years – N/A

Healthy volunteers: No

Phase: NA

Enrollment: 30

Sponsor: National Cancer Institute, Egypt

Summary

This study aims to compare the reduction in knee pain between ultrasound-guided cryoneurolysis and bipolar radiofrequency ablation (RFA), as measured by the Numerical Rating Scale (NRS) at predefined follow-up intervals.

Eligibility Criteria

Inclusion Criteria: * Age ≥ 40 years * Symptomatic knee osteoarthritis (OA) in bladder cancer patient \[based on American College of Radiology (ACR) criteria\] * Radiological OA (Kellgren-Lawrence grade III-IV) * Chronic knee pain ≥ 3-6 months * Numerical Rating Scale (NRS) ≥ 5 despite conservative treatment * Positive diagnostic genicular nerve block (\>50% pain relief). Exclusion Criteria: * Prior genicular nerve ablation * Coagulopathy * Local infection * Severe deformity * Neuropathic pain syndromes * Uncontrolled comorbidities

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View on ClinicalTrials.gov

Source: ClinicalTrials.gov (NCT07855367). StuddyBuddy aggregates publicly available trial information.