Effect of Ventilator Hyperinflation Combined With Body Positioning on ABG in VAP

Conditions: Ventilator Associated Bacterial Pneumonia (VABP), Critical Illness

Sex: All

Ages: 40 Years – 60 Years

Healthy volunteers: No

Phase: NA

Enrollment: 40

Sponsor: Al-Zaytoonah University of Jordan

Summary

This study aims to evaluate the effect of ventilator hyperinflation combined with body positioning on arterial blood gases in patients with ventilator-associated pneumonia. Forty-two mechanically ventilated patients will be randomly assigned into two groups receiving the intervention in either supine or lateral decubitus positions. Arterial blood gases will be assessed over a 6-day intervention period. The findings are expected to provide evidence regarding the optimal positioning strategy to enhance the effectiveness of ventilator hyperinflation in improving gas exchange in critically ill patients.

Eligibility Criteria

Inclusion Criteria: * Mechanically ventilated patients ≥ 48 hours * Diagnosed with VAP (clinical + chest X-ray) * Age: 40-60 years * Hemodynamically stable * Unilateral lung involvement Exclusion Criteria: * Bilateral lung disease * Unstable cardiovascular conditions * Contraindications to positioning * Re-intubation cases * Presence of pneumothorax or air leak

Interested in this study? View the official listing for contact and enrollment details.

View on ClinicalTrials.gov

Source: ClinicalTrials.gov (NCT07854730). StuddyBuddy aggregates publicly available trial information.