Join us at Health Research Day — June 6th at Canton Waterfront Park, Baltimore!   Learn More →
← Back to all trials
Not Yet Recruiting NCT07850947

An Observational Study of Percutaneous Glomerular Filtration Rate (TGFR) in the Early Warning of Contrast-induced Acute Kidney Injury During the Peri-examination Period of Emergency Enhanced CT

Conditions: Contrast-associated Acute Kidney Injury

Sex: All
Ages: 18 Years – N/A
Healthy volunteers: No
Enrollment: 30
Sponsor: Second Affiliated Hospital, Zhejiang University, School of Medicine

Location: The Second Affiliated Hospital, Zhejiang University School of Medicine Hangzhou Zhejiang

Summary

This is a single-center, prospective observational study. We aim to evaluate the performance of transdermal glomerular filtration rate (TGFR) compared with baseline estimated glomerular filtration rate (eGFR) for early prediction of contrast-associated acute kidney injury (CA-AKI) in emergency patients scheduled for contrast-enhanced CT. Eligible participants are adult emergency patients with baseline eGFR between 15 and 120 mL/min/1.73m². TGFR monitoring will be performed during the peri-contrast CT period. We will collect clinical and laboratory data and follow up renal function after contrast exposure to analyze the predictive value of TGFR for CA-AKI. No extra therapeutic interventions will be applied in this study.

Eligibility Criteria

Inclusion Criteria: 1. Aged ≥18 years old. 2. Undergoing emergency contrast-enhanced CT examination. 3. Patients who agree to participate in this observational study. Exclusion Criteria: 1. History of end-stage renal disease receiving renal replacement therapy. 2. Known allergy to iodinated contrast media. 3. Pregnancy. 4. Unable to complete 72-hour follow-up after contrast administration.

Interested in this study? View the official listing for contact and enrollment details.

View on ClinicalTrials.gov

Source: ClinicalTrials.gov (NCT07850947). StuddyBuddy aggregates publicly available trial information.