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Not Yet Recruiting NCT07844408

Study of Eye Fatigue From Digital Screens and Its Impact on Visual Performance in People With Normal Vision and Myopia, With and Without Dry Eye Symptoms and Signs

Conditions: Myopia, Dry Eye Disease (DED)

Sex: All
Ages: 18 Years – 35 Years
Healthy volunteers: Yes
Phase: NA
Enrollment: 120
Sponsor: Essilor International

Location: Center of Neurosciences and Medical Research Essilor International Paris Paris

Summary

The goal of this observational study is to investigate the effects of eye fatigue induced by screen task on dry eye disease (DED) signs and symptoms, visual performance, and visual behavior in young adults with and without DED and with normal vision and myopia. The main questions it aims to answer are: * Does a screen task that induces eye fatigue affect dry eye signs and symptoms, visual quality, and visual behavior? * Are the effects of this screen task different in individuals with and without DED, and are they associated with myopia? Researchers will compare participants with and without DED to determine whether they respond differently to a screen task designed to induce eye fatigue. They will also explore potential relationships between DED and myopia. Participants will: * Attend two study visits. * Complete eligibility screening and realize visual and eye assessments. * Be classified as having or not having DED based on a questionnaire and clinical eye examinations. * Perform a screen task designed to induce eye fatigue. * Perform measurements before and after a screen task, including assessments of DED signs and symptoms, blinking behavior, eye movements, visual performance, and physiological responses with a smartwatch.

Eligibility Criteria

Inclusion Criteria: * A willing participant who speaks French fluently, is willing to follow the protocol, is able to read and understand the informed consent form, and can give their free and informed consent; * Age between 18 and 35 years * Daily screen use of more than 4 hours * Monocular and binocular distance and near visual acuity of 0.1 logMAR or better (equivalent to 20/25 Snellen or 8/10) with best optical correction * Emmetropic groups: * Spherical equivalent (SE): -0.50 D \< SE ≤ +0.50 D * Regular astigmatism (cylinder) 0.75 D (absolute value) * Anisometropia 1.00 D * Myopic groups: * Spherical equivalent (SE): -5.00 D ≤ SE ≤ -0.50 D * Regular astigmatism (cylinder) 0.75 D (absolute value) * Anisometropia 1.50 D * Groups with signs and symptoms of DED: * OSDI-6 questionnaire score ≥ 4 * NIBUT \12 hours per day); * Use of medications that may influence vision or interfere with study assessments (e.g., antidepressants, tranquilizers, antipsychotics, oral retinoids, or medications with atropinic effects); * Ophthalmic treatments, light therapy, or other treatments for dry eye disease within the past 3 months, with the exception of over-the-counter eye drops not requiring a prescription, such as hyaluronic acid-based lubricants.

Interested in this study? View the official listing for contact and enrollment details.

View on ClinicalTrials.gov

Source: ClinicalTrials.gov (NCT07844408). StuddyBuddy aggregates publicly available trial information.