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Recruiting NCT07841249

Cardiorespiratory Fitness After Lobectomy Versus Sublobar Resection

Conditions: Lung Cancer (NSCLC)

Sex: All
Ages: 18 Years – N/A
Healthy volunteers: No
Enrollment: 604
Sponsor: Tongji Hospital

Location: Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology Wuhan Hubei

Summary

This observational study will compare changes in cardiorespiratory fitness after lobectomy and sublobar resection. Sublobar resection includes segmentectomy and wedge resection. Patients who can undergo pulmonary resection and meet the eligibility criteria will be studied during routine clinical care; the research will not assign the surgical procedure or add a study-specific intervention. Cardiopulmonary exercise testing (CPET) and pulmonary function testing will be performed before surgery and at routine follow-up visits 6 and 12 months after surgery. Changes from the preoperative assessment will be compared within each surgical group and between the two groups. The study will also examine the relationship between CPET measurements and postoperative complications.

Eligibility Criteria

Inclusion Criteria: 1\. Able to understand the study and provide written informed consent. 2. Considered able to tolerate surgical treatment, including segmentectomy, lobectomy, or wedge resection, following preoperative assessment, including cardiac and pulmonary function testing. \- Exclusion Criteria: 1. Pregnant or breastfeeding. 2. Any absolute contraindication to CPET. 3. A history of severe heart disease, heart failure, myocardial infarction, or an episode of angina within the previous 3 months. 4. A cerebrovascular event, including cerebral infarction or cerebral hemorrhage, within the previous 3 months. 5. A psychiatric illness that prevents communication. 6. Unable to cooperate with the examinations. -

Interested in this study? View the official listing for contact and enrollment details.

View on ClinicalTrials.gov

Source: ClinicalTrials.gov (NCT07841249). StuddyBuddy aggregates publicly available trial information.