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Recruiting NCT07841158

Histological and Histomorphometric Assessment With Inflammatory Profile Analysis of Bone Tissue After Horizontal Ridge Augmentation Using Customized Porous Zirconia Shell

Conditions: Alveolar Bone Loss, Alveolar Ridge Deficiency

Sex: All
Ages: 21 Years – N/A
Healthy volunteers: No
Phase: NA
Enrollment: 10
Sponsor: Mohammed Mahmoud Abed

Location: October University for Modern Sciences and Arts (MSA), Faculty of Dentistry Giza Giza Governorate

Summary

The goal of this clinical study is to learn whether a custom-made porous zirconia shell can support good-quality new bone when widening the lower back jaw before dental implant placement. The study includes adults whose jawbone in this area is too narrow for implants (Seibert Class I defects). The main question it aims to answer is: What is the quality of the new bone formed under a porous zirconia shell, and how much inflammation does the tissue show? Participants will: * Receive gum treatment and a CBCT scan before surgery * Have bone augmentation surgery, in which a digitally designed porous zirconia shell is fixed over a mixture of their own bone and xenograft * Return after 2 weeks for suture removal and a check of the wound * Return after 6 months for a CBCT scan, removal of the shell, collection of a small bone sample (biopsy), and dental implant placement

Eligibility Criteria

Inclusion Criteria: * Age more than 21 years old * Horizontal bone loss in the lower posterior area (Seibert Class I) * Enough inter-arch space for placement of implant-supported prosthesis * Motivated patient to have the treatment * Good oral hygiene Exclusion Criteria: * Patients with systemic conditions that could interfere with the healing process * Pregnant females * Smokers * Poor oral hygiene

Interested in this study? View the official listing for contact and enrollment details.

View on ClinicalTrials.gov

Source: ClinicalTrials.gov (NCT07841158). StuddyBuddy aggregates publicly available trial information.