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NCT07841158
Histological and Histomorphometric Assessment With Inflammatory Profile Analysis of Bone Tissue After Horizontal Ridge Augmentation Using Customized Porous Zirconia Shell
Conditions: Alveolar Bone Loss, Alveolar Ridge Deficiency
Sex: All
Ages: 21 Years – N/A
Healthy volunteers: No
Phase: NA
Enrollment: 10
Sponsor: Mohammed Mahmoud Abed
Location: October University for Modern Sciences and Arts (MSA), Faculty of Dentistry Giza Giza Governorate
Summary
The goal of this clinical study is to learn whether a custom-made porous zirconia shell can support good-quality new bone when widening the lower back jaw before dental implant placement. The study includes adults whose jawbone in this area is too narrow for implants (Seibert Class I defects).
The main question it aims to answer is: What is the quality of the new bone formed under a porous zirconia shell, and how much inflammation does the tissue show?
Participants will:
* Receive gum treatment and a CBCT scan before surgery
* Have bone augmentation surgery, in which a digitally designed porous zirconia shell is fixed over a mixture of their own bone and xenograft
* Return after 2 weeks for suture removal and a check of the wound
* Return after 6 months for a CBCT scan, removal of the shell, collection of a small bone sample (biopsy), and dental implant placement
Eligibility Criteria
Inclusion Criteria:
* Age more than 21 years old
* Horizontal bone loss in the lower posterior area (Seibert Class I)
* Enough inter-arch space for placement of implant-supported prosthesis
* Motivated patient to have the treatment
* Good oral hygiene
Exclusion Criteria:
* Patients with systemic conditions that could interfere with the healing process
* Pregnant females
* Smokers
* Poor oral hygiene
Source: ClinicalTrials.gov (NCT07841158). StuddyBuddy aggregates publicly available trial information.