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Not Yet Recruiting NCT07839936

A Study of VERVE-102 (LY4636581) in Adults With or at High Risk for Cardiovascular Disease

Conditions: Atherosclerosis, Cardiovascular Disease, Hypercholesterolemia

Sex: All

Ages: 18 Years – 70 Years

Healthy volunteers: No

Phase: PHASE2

Enrollment: 175

Sponsor: Verve Therapeutics, Inc.

Location: Epic Medical Research DeSoto Texas

Summary

The purpose of this study is to measure the change in bad cholesterol (LDL-C) with VERVE-102 compared to placebo in adults who have plaque buildup in their arteries or are at high risk of developing it.

Eligibility Criteria

Inclusion Criteria: * Established atherosclerotic cardiovascular disease (ASCVD) and/or at a high risk of ASCVD Exclusion Criteria: * History of confirmed or suspected homozygous familial hypercholesterolemia (HoFH) * Chronic liver disease * Current treatment with PCSK9 inhibitor or prior treatment within specified timeframe

Interested in this study? View the official listing for contact and enrollment details.

View on ClinicalTrials.gov

Source: ClinicalTrials.gov (NCT07839936). StuddyBuddy aggregates publicly available trial information.