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NCT07836153
Mechanical Power and Mortality in Mechanically Ventilated Adults
Conditions: Mechanical Ventilation Complication, Ventilator Induced Lung Injury, ARDS, ICU Mortality (Survival Rate)
Sex: All
Ages: 18 Years – N/A
Healthy volunteers: No
Enrollment: 116
Sponsor: Zagazig University
Location: Surgical Intensive Care Unit, Zagazig University Hospitals Zagazig Sharqia Province
Summary
This prospective observational cohort study aims to investigate the relationship between mechanical power during the first 72 hours of invasive mechanical ventilation and 28-day mortality in mechanically ventilated adult patients admitted to the Surgical Intensive Care Unit at Zagazig University Hospitals.
Eligibility Criteria
Inclusion Criteria:
* Age ≥18 years.
* Both sexes.
* Patients requiring invasive controlled mechanical ventilation in the ICU and expected to require mechanical ventilation for at least 72 hours.
* Enrollment within the first 8 hours after initiation of invasive mechanical ventilation.
* Acceptance and written informed consent from a first-degree relative.
Exclusion Criteria:
* Predominant spontaneous breathing or weaning modes during the first 48 hours.
* Severe hemodynamic instability precluding standardized measurements.
* Prolonged mechanical ventilation prior to ICU admission.
* Pregnancy.
* Chest trauma.
Source: ClinicalTrials.gov (NCT07836153). StuddyBuddy aggregates publicly available trial information.
