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Recruiting NCT07826741

Intrathecal Morphine and Transversalis Fascia Plane Block for Analgesia After Open Inguinal Hernia Repair

Conditions: Pain, Postoperative, Inguinal Hernia Unilateral, Intrathecal Morphine, Transversalis Fascia Plane Block, Multimodal Analgesia

Sex: All
Ages: 18 Years – 80 Years
Healthy volunteers: No
Phase: NA
Enrollment: 90
Sponsor: Atatürk Chest Diseases and Chest Surgery Training and Research Hospital

Location: Ankara Etlik City Hospital Yenimahalle Ankara

Summary

Inguinal hernia is a common surgical condition, and open inguinal hernia repair may be associated with significant postoperative pain. Inadequate pain control can delay early mobilization, reduce patient comfort, and increase the need for opioid analgesics. Therefore, effective postoperative pain management is an important component of perioperative care. Several analgesic strategies can be used after open inguinal hernia repair, including systemic multimodal analgesia, neuraxial opioids, and regional anesthesia techniques. Intrathecal morphine can provide prolonged postoperative analgesia but may be associated with opioid-related adverse effects such as nausea, vomiting, pruritus, urinary retention, and respiratory depression. Ultrasound-guided transversalis fascia plane block is a regional anesthesia technique designed to provide analgesia to the inguinal region while potentially reducing systemic opioid requirements. The aim of this prospective, randomized, assessor-blinded, controlled trial is to compare the postoperative analgesic efficacy of intrathecal morphine, transversalis fascia plane block, and spinal anesthesia alone in adult patients undergoing elective open unilateral inguinal hernia repair.

Eligibility Criteria

Inclusion Criteria: * Age between 18 and 80 years * American Society of Anesthesiologists physical status I-II-III * Body mass index between 18 and 30 kg/m² * Patients undergoing elective open inguinal hernia repair Exclusion Criteria: * Patient refusing the procedure * History of chronic analgesic or opioid therapy * History of local anesthetic and morphine allergy * Infection in the intervention area

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View on ClinicalTrials.gov

Source: ClinicalTrials.gov (NCT07826741). StuddyBuddy aggregates publicly available trial information.