A Plant-Based Diet in the Treatment of Coronary Microvascular Dysfunction

This study will evaluate whether a fully provided, unrefined, polyphenol-rich plant-based diet can improve blood vessel function in adults with coronary microvascular dysfunction (CMD), a condition that causes reduced blood flow in the small vessels of the heart despite the absence of major coronary artery blockages. Participants will follow the diet for 12 weeks while continuing their usual medical care. Researchers will assess changes in vascular function, symptoms, blood pressure, blood lipids, and other health measures throughout the study. Participants have up to 60 days after consent to complete screening and pre-intervention baseline assessments, potentially over two visits. Day 0 is counseling/education, and diet initiation. Weeks 4, 8, and 12 are measured from Day 0.

Inclusion Criteria: * Women must be postmenopausal. * History of angina, ischemic symptoms, or symptoms consistent with ischemia in the absence of obstructive coronary artery disease. * No obstructive coronary artery disease (\0.80). * Clinically documented coronary microvascular dysfunction (CMD), including coronary flow reserve \