The Use of Single-Beat TE-e' in Evaluation of Left Atrial Pressure in Critically Ill Patients: The TELAP-ICU Trial

Conditions: Critical Illness, Elevated Left Atrial Pressure, Left Ventricular Diastolic Dysfunction, Echocardiography

Sex: All

Ages: 18 Years – N/A

Healthy volunteers: No

Enrollment: 50

Sponsor: Queen Mary Hospital, Hong Kong

Summary

This study evaluates a new single-beat echocardiographic technique (TE-e', the time difference between the onset of the mitral inflow E wave and the septal e' wave on tissue Doppler imaging) for estimating left atrial pressure (LAP) in critically ill patients, comparing it against the standard two-beat method. The goal is to determine whether the faster, single-beat method gives results as reliable as the conventional method, and whether it can help identify patients with elevated left atrial pressure without an invasive procedure.

Eligibility Criteria

Inclusion Criteria: * Adult patients ≥18 years admitted to the QMH Adult Intensive Care Unit (AICU) * Requiring a transthoracic echocardiogram (TTE) as part of routine clinical care * TE-e' obtainable by both the conventional and the novel method Exclusion Criteria: * Patients \

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View on ClinicalTrials.gov

Source: ClinicalTrials.gov (NCT07820319). StuddyBuddy aggregates publicly available trial information.