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NCT07817524
Clinical Outcome of Coronary Artery Bypass Graft Surgery Versus Percutaneous Coronary Intervention in Patients With Severe Left Ventricular Disfunction (CROWN)
Conditions: Coronary Artery Disease, Left Ventricular Cardiac Dysfunction
Sex: All
Ages: 18 Years – N/A
Healthy volunteers: No
Enrollment: 300
Sponsor: Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Location: Fondazione Policlinico Universitario A Gemelli IRCCS Roma
Summary
The objective of this study is to evaluate the best treatment strategy in patients with critical coronary artery disease and severe left ventricular dysfunction.
In details, main goal of the study is to compare the clinical outcomes of patients with critical coronary artery disease and severe left ventricular dysfunction undergoing surgical coronary artery bypass grafting with those of patients treated by percutaneous coronary intervention.
Eligibility Criteria
Inclusion Criteria:
* Age \>= 18 years old;
* Written informed consent;
* Indication to CABG surgery (both "on-pump" and "off-pump") or to PCI;
* Preoperative EF ≤35%.
Exclusion Criteria:
* Inability to give written informed consent;
* Emergency surgery;
* Combined cardiac surgical procedures;
* Previous cardiac surgery.
Source: ClinicalTrials.gov (NCT07817524). StuddyBuddy aggregates publicly available trial information.
