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Completed
NCT07810985
Bismuth Quadruple Therapy Versus Modified Bismuth Therapy for Helicobacter Pylori
Conditions: Helicobacter Eradication
Sex: All
Ages: 18 Years – 70 Years
Healthy volunteers: No
Phase: PHASE3
Enrollment: 200
Sponsor: Reham Abdelkader Elkhouly
Location: Tanta university Tanta Algharbia
Summary
The primary objective of the study is to compare the efficacy of 2 different regimens of treatment of gastric bacteria (H pylori) these are: quadruple bismuth therapy and clarithromycin triple therapy with add-on bismuth, in eradicating H. pylori.
The secondary objective of the study is detection of adverse effects and treatment compliance in both regimens.
Eligibility Criteria
Inclusion Criteria:
* Patients aged ≥ 18 years.
* Confirmed diagnosis of H. pylori infection.
Exclusion Criteria:
* Pregnant or lactating women.
* Prior treatment for H. pylori infection.
* History of antibiotic or PPI use within the month preceding enrollment.
* History of hypersensitivity or allergic reaction to any of the study drugs.
* Presence of any contraindication to the study medications.
* Advanced chronic liver disease or renal disease.
Source: ClinicalTrials.gov (NCT07810985). StuddyBuddy aggregates publicly available trial information.
