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Recruiting NCT07809425

External Oblique Intercostal Block With or Without Intravenous Lidocaine Infusion for Analgesia in Patients Undergoing Gastric Bypass Surgery

Conditions: Obese Patients

Sex: All
Ages: 18 Years – 60 Years
Healthy volunteers: No
Phase: NA
Enrollment: 100
Sponsor: Menoufia University

Location: Faculty of Medicine Alexandria

Summary

Adding a perioperative lidocaine infusion (1.5 mg/kg loading + 1.5 mg/kg/h) to bilateral EOIB and low dose fentanyl loading reduces intraoperative fentanyl consumption (ANI guided rescue) compared to placebo, without increasing adverse events.

Eligibility Criteria

Inclusion Criteria: * Age 18-60 years. * BMI ≥ 35 kg/m². * ASA physical status II or III. * Scheduled for elective laparoscopic Roux en Y gastric bypass. * Ability to provide written informed consent. Exclusion Criteria: * Refusal. * Allergy or contraindication to lidocaine, fentanyl, ropivacaine, or any study medication. * Chronic opioid use or dependence. * Significant hepatic (AST/ALT\> 3× normal, cirrhosis) or renal impairment (CrCl\< 30 mL/min). * Second or third degree AV block or significant bradyarrhythmia without pacemaker. * Coagulopathy, anticoagulation incompatible with regional anesthesia, or infection at block site. * Pregnancy or lactation. * Severe psychiatric or cognitive disorder. * Failed bilateral EOIB (absence of sensory loss in T6-T10 after 30 min) - excluded from analysis.

Interested in this study? View the official listing for contact and enrollment details.

View on ClinicalTrials.gov

Source: ClinicalTrials.gov (NCT07809425). StuddyBuddy aggregates publicly available trial information.