HD-tACS for Alcohol Use Disorder

This study aims to systematically explore the effectiveness of accelerated HD-tACS in treating AUD, particularly its efficacy in reducing alcohol craving and preventing relapse in AUD patients.

Inclusion Criteria: * Age range: 18-55 years old, gender not restricted; * Meets the DSM-5 diagnostic criteria for alcohol use disorder (moderate to severe); * AUDIT score ≥ 16; * Baseline score after alcohol cue-induced stimulation is ≥ 3; * Completed detoxification treatment before enrollment (moderate to severe), with detoxification duration of ≥ 7 days and ≤ 90 days; * Has a primary school education or above, and can understand and complete the research assessment; * Voluntarily participated in the study and signed the informed consent form. Exclusion Criteria: * Currently, there are other substance use disorders (except nicotine); * Currently, there are schizophrenia, bipolar disorder or other severe psychotic disorders; * Has a history of epilepsy or family history of epilepsy; * Has a history of brain trauma, brain surgery or intracranial metal implants; * Has received electroconvulsive therapy (ECT), transcranial electrical/magnetic/ultrasound stimulation within the past 6 months; * Pregnant or lactating women; * Other situations that the researchers consider unsuitable for participation in this study.