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Completed NCT07806539

Hemodynamic Monitoring-Guided Goal-Directed Fluid Therapy in Robotic Radical Prostatectomy

Conditions: Prostate Cancer, Robotic Radical Prostatectomy

Sex: Male
Ages: 18 Years – 80 Years
Healthy volunteers: No
Enrollment: 48
Sponsor: Antalya Training and Research Hospital

Location: Antalya Training and Research Hospital Antalya

Summary

This prospective observational cohort study evaluated goal-directed fluid therapy guided by minimally invasive hemodynamic monitoring in adult male patients undergoing elective robotic radical prostatectomy. Patients were prospectively enrolled and followed according to the intraoperative fluid management strategy used in routine clinical practice. Patients managed with LiDCO®Rapid-guided goal-directed fluid therapy constituted the hemodynamic monitoring-guided group, while patients managed with conventional intraoperative fluid therapy constituted the control group. No randomization or additional research-related intervention was performed. The study compared the two fluid management strategies with respect to intraoperative crystalloid fluid administration and selected perioperative clinical and laboratory parameters.

Eligibility Criteria

Inclusion Criteria: * Male patients aged 18 to 80 years * Patients scheduled for elective robotic radical prostatectomy * American Society of Anesthesiologists physical status I-III * Patients who provide written informed consent Exclusion Criteria: * Refusal to participate in the study * Cardiac rhythm disturbances * Severe left ventricular dysfunction, defined as ejection fraction \2 mg/dL * Hemoglobin \40 kg/m² * Major peripheral vascular disease * Implanted pacemaker or implantable cardioverter-defibrillator * Chronic obstructive pulmonary disease * Conditions associated with increased intra-abdominal pressure * Emergency surgery

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View on ClinicalTrials.gov

Source: ClinicalTrials.gov (NCT07806539). StuddyBuddy aggregates publicly available trial information.