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NCT07803458
Attention-based Binocular Training for Impaired Stereopsis (BRAVE)
Conditions: Amblyopia, Strabismus, Anisometropia, Binocular Vision Abnormalities, Binocular Vision Disorder
Sex: All
Ages: 18 Years – 39 Years
Healthy volunteers: Yes
Phase: NA
Enrollment: 56
Sponsor: Centre for Eye and Vision Research
Location: Centre for Eye and Vision Research Limited Hong Kong Hong Kong SAR
Summary
This study evaluates a novel attention-based binocular visual search training paradigm designed to improve stereopsis (stereo vision) in individuals with impaired binocular vision. Disruptions in balanced binocular input, such as from strabismus or anisometropia, often lead to deficient stereo vision, causing daily visuomotor limitations. While traditional therapies focus on monocular acuity, they frequently fail to restore stereopsis, especially in adults. The investigators propose a unique dichoptic visual search training method that embeds binocular disparity inside an attention-demanding task, encouraging cooperative binocular integration. Participants aged 18-39 with impaired stereopsis will be randomly assigned in a 1:1 ratio to either the active training group (disparity-embeded task) or the active control group (identical task with zero disparity). Both groups complete 5 training sessions over 5-6 weeks. Assessments will occur at baseline, immediately post-training, and at a 12-week follow-up. The primary objective is to determine if the active training group shows significantly greater improvements in local stereoacuity compared to the control group.
Eligibility Criteria
Inclusion Criteria:
* Aged 18-39 years (inclusive).
* Deficient or anomalous stereoscopic vision with a stereoacuity \>= 70 sec arc or unmeasurable stereoacuity.
* Best corrected visual acuity (BCVA) of \< 0.80 logMAR in both eyes, with at least one eye having a visual acuity of \
Source: ClinicalTrials.gov (NCT07803458). StuddyBuddy aggregates publicly available trial information.