Examination of Rectal Blood Supply During Rectal Cancer Surgery Using Laser Speckle Contrast Imaging

Conditions: Rectal Cancer, Total Mesorectal Excision, Laser Speckle Contrast Imaging, Indocyanine Green (ICG), Optical Imaging

Sex: All

Ages: 18 Years – N/A

Healthy volunteers: No

Phase: NA

Enrollment: 100

Sponsor: University of Aarhus

Summary

This multicentre feasibility study evaluates the feasibility of performing laparoscopic Laser Speckle Contrast Imaging (LSCI) measurements of rectal perfusion during rectal cancer surgery. To our knowledge, LSCI has not previously been applied laparoscopically for intraoperative assessment of rectal perfusion in this setting. Laparoscopic LSCI measurements will be compared with indocyanine green fluorescence imaging, and associations between quantitative measures of colorectal perfusion and postoperative outcomes, including anastomotic leakage, will be explored.

Eligibility Criteria

Inclusion Criteria: * Age ≥ 18 years * Rectal cancer * Surgical strategy either partial or total mesorectal excision * Able to provide informed consent Exclusion Criteria: \- Allergy to iodine

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View on ClinicalTrials.gov

Source: ClinicalTrials.gov (NCT07799740). StuddyBuddy aggregates publicly available trial information.