Tuberculosis Sentinel Research Network (TB-SRN)

The overarching objective/aim of the study is to assess pulmonary TB treatment and longer-term outcomes among people with and without HIV in African population in order to inform policy and practice around TB treatment and create a platform for additional TB research in Zambia

Inclusion Criteria: * 1\. Be ≥15 years of age * Clinically diagnosed pulmonary TB and initiated/to be initiated on anti-TB treatment, as determined by medical providers through standard of care, on the basis of either. * Microbiologically confirmed pulmonary TB based on sputum or other respiratory samples with either Exclusion Criteria: * Have plans to follow-up for TB care at a site distant from the enrollment site, imminent plans to move from his/her current area of residence, or plans to return to a distant area of residence, which would interfere with the participant's ability to complete all study visits (through the 12-month post-treatment visit). * 1\. Received \>1 week of TB treatment within the prior 30 days, excluding TB preventive therapy * 3\. Have substantial cognitive impairment that in the opinion of the site investigator or designee may interfere with the ability to give reliable informed consent