Microneedling With Glycolic Acid or Trichloroacetic Acid for Atrophic Acne Scars

Atrophic acne scars are depressed scars that can remain after acne has healed. Microneedling is a procedure that uses very small needles to create controlled micro-injuries in the skin, which may stimulate collagen production and improve scar appearance. Chemical peels, including glycolic acid and trichloroacetic acid, may also improve acne scars. This study compares three approaches for treating atrophic acne scars: microneedling followed by a 35% glycolic acid peel, microneedling followed by a 15% trichloroacetic acid peel, and microneedling alone. Sixty adults with atrophic acne scars are randomly assigned to one of the three groups. Participants receive a series of microneedling treatments at 2-week intervals. The study evaluates changes in scar severity, participant satisfaction, treatment-related pain, recovery time after treatment, and side effects. The findings may help identify whether adding either chemical peel to microneedling provides greater benefit than microneedling alone and whether one combination has a shorter recovery time or fewer side effects.

Inclusion Criteria: * Adults of either sex aged 18 years or older. * Presence of atrophic acne scars of any type or duration. * Fitzpatrick skin type I to IV. Exclusion Criteria: * Active inflammatory acne lesions, skin infection, or a tendency to develop keloids. * Immunocompromised state, facial cancer, or severely damaged facial skin. * Known hypersensitivity to glycolic acid or trichloroacetic acid. * Oral isotretinoin use within 6 months before enrollment. * Pregnancy or breastfeeding. * Inability or unwillingness to adhere to study procedures. * Unrealistic expectations regarding treatment outcomes.