Join us at Health Research Day — June 6th at Canton Waterfront Park, Baltimore!   Learn More →
← Back to all trials
Not Yet Recruiting NCT07796321

Effort of Breathing and Dyssynchrony Burden During Assisted Ventilation in Paediatric Patients

Conditions: Mechanical Ventilation, Paediatric Intensive Care, Paediatric Dysfunctional Breathing

Sex: All
Ages: N/A – 18 Years
Healthy volunteers: No
Phase: NA
Enrollment: 25
Sponsor: The Hospital for Sick Children

Location: The Hospital for Sick Children (SickKids) Toronto Ontario

Summary

The goal of this trial is to learn if one mode of mechanical ventilation (i.e. machine to help with breathing) is better than another in children who need help from a machine to breathe. The main questions it aims to answer are: * How hard do children need to work to breathe when they are using different types of modes of mechanical ventilation? * Evaluate which mode of mechanical ventilation performs better when the patient is clinically awake enough to start breaths

Eligibility Criteria

Inclusion Criteria: 1. Consent provided 2. Aged: birth to 18 years of age 3. Invasively mechanically ventilated and expected to remain intubated for ≥ 6 hours, in the ventilator weaning phase. Exclusion Criteria: 1. Contraindication for esophageal catheter placement such as esophageal repair (e.g. esophageal surgery or esophageal varices) 2. On Extracorporeal Membrane Oxygenation (ECMO) 3. Undergoing assessment for brain death or brain death confirmed 4. Patients with a severe systemic disease that poses a constant threat to their life: * \20% within the last 24 hrs * increase in ventilation support or an FiO2 change ≥30% within the last 24 hrs * most responsible physician (MRP) determine patient is not eligible for the study intervention

Interested in this study? View the official listing for contact and enrollment details.

View on ClinicalTrials.gov

Source: ClinicalTrials.gov (NCT07796321). StuddyBuddy aggregates publicly available trial information.