Dietary Fibre Supplementation to Delay Disease Progression in Early Prostate Cancer

This qualitative research study, based on semi-structured interviews and a focus group, aims to explore the attitudes of prostate cancer patients on active surveillance (AS) towards dietary fibre supplementation, given the potential benefits demonstrated in previous research. Prostate cancer patients on AS, often overlooked in the literature, experience cyclical anxiety, particularly regarding disease progression. Lifestyle modifications, including dietary changes, are pursued by a number of these patients as a preventative measure. Dietary fibre such as inulin and psyllium have promising results in studies of pelvic cancers. However, it is important to note that these findings do not directly apply to patients who are currently undergoing AS for prostate cancer. Despite potential side effects, these dietary fibres may contribute to anti-inflammatory and antitumorigenic effects. Building on this evidence, we aim to explore patient perspectives on the feasibility and acceptability of dietary fibre supplementation during AS. The insights gained will guide the development of a feasibility and/or pilot studies and, subsequently, a multicentre randomised controlled trial. If successful, this intervention could potentially reshape clinical practice for patients with prostate cancer on AS.

Inclusion Criteria: 1. Participants over 18 years of age. 2. Participants with residence in North-East Scotland. 3. Participants must be fluent in the English language. 4. Participants on active surveillance. Exclusion Criteria: 1. Participants who do not speak fluent English will be excluded from this study. 2. Participants who were treated with surgery, radiotherapy, chemotherapy or anti-androgen therapy for their prostate cancer. 3. Vulnerable participants, classified as adults who do not have the capacity to consent for themselves, will not be included in the study. If the research team are made aware that someone has lost capacity then they will be withdrawn from the study.