Effect of NeoSEALER FLO and AH Plus Resin Sealer on Postoperative Pain and Healing of Periapical Lesions

Tissue repair is an essential process that reestablishes tissue integrity and regular function. Nevertheless, different therapeutic factors and clinical conditions may interfere in this process of periapical healing.The success of root canal treatment is affected by the correct choice of clinical protocol. These factors are dependent on the sanitization process (instrumentation, irrigating solution, irrigating strategies, and intracanal dressing) the apical limit of the root canal preparation and obturation, and the quality of the sealer. The challenges affecting the healing process of endodontically treated teeth include control of the inflammation of pulp or infectious processes and simultaneous neutralization of unpredictable provocations to the periapical tissue.

Inclusion Criteria: * Patients with mature permanent teeth. * Patients with apical periodontitis. * Maxillary anterior teeth only will be involved. * Patients should be free from any systemic disease that may affect normal healing and predictable outcome. * Patients who will agree to the consent and will commit to follow-up period. * The selected teeth should have periapical lesion score ≤3 Exclusion Criteria: * Patients with immature canals. * Patients with swelling. * Pregnant females. * Patients who could/would not participate in a 1-year follow-up. * Geriatric patients. * Patients with old age. * Teeth with periodontal involvement. * Teeth with vertical root fractures. * Non-restorable teeth. * cases with previously initiated endodontic treatment.