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Recruiting NCT07781878

Skin Staples vs Polypropylene in Elective Laparotomy

Conditions: Surgical Site Infection

Sex: All
Ages: 15 Years – 50 Years
Healthy volunteers: Yes
Phase: NA
Enrollment: 130
Sponsor: Pakistan Institute of Medical Sciences

Location: Pakistan Institute of Medical Sciences Islamabad Capital

Summary

Surgical site infection (SSI) is one of the most common postoperative complications following elective laparotomy and contributes significantly to patient morbidity, prolonged hospital stay, and increased healthcare costs. Various techniques are available for skin closure, including skin staples and polypropylene sutures; however, evidence regarding their comparative effectiveness remains inconsistent, particularly in low- and middle-income countries. This randomized controlled trial aims to compare skin staples with polypropylene sutures for skin closure following elective laparotomy. Eligible adult patients undergoing elective laparotomy at the Department of General Surgery, Pakistan Institute of Medical Sciences (PIMS), Islamabad, will be randomly allocated in a 1:1 ratio to receive either skin staples or polypropylene sutures. The primary outcomes are skin closure time and incidence of surgical site infection within 30 days of surgery. Secondary outcomes include wound dehiscence, postoperative pain, cosmetic scar appearance, patient satisfaction, and duration of hospital stay. The findings will provide evidence regarding the optimal skin closure technique for elective laparotomy in the Pakistani population.

Eligibility Criteria

Inclusion Criteria: Age 15-50 years Elective laparotomy ASA I-III Written informed consent Male or female Exclusion Criteria: Emergency surgery Previous SSI Recurrent surgery BMI \30 kg/m² Haemoglobin \

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View on ClinicalTrials.gov

Source: ClinicalTrials.gov (NCT07781878). StuddyBuddy aggregates publicly available trial information.