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NCT07781683
Clinical Evaluation of Salivary 1,5-Anhydroglucitol in Diabetes
Conditions: Type 2 Diabetes (T2DM)
Sex: All
Ages: 18 Years – 80 Years
Healthy volunteers: No
Enrollment: 180
Sponsor: Shanghai 6th People's Hospital
Location: Shanghai Sixth People's Hospital Shanghai Shanghai Municipality
Summary
The goal of this observational study is to evaluate the clinical value of salivary 1,5-anhydroglucitol (1,5-AG) and assess a novel noninvasive detection approach in individuals with and without type 2 diabetes. Additionally, the study will examine the relationships of salivary 1,5-AG with serum 1,5-AG and continuous glucose monitoring (CGM) measures of short-term glycemic control and fluctuations.
Eligibility Criteria
Inclusion Criteria:
1. Aged between 18 and 80 years.
2. Individuals without a history of diabetes, or patients with type 2 diabetes mellitus.
Exclusion Criteria:
1. History of systemic glucocorticoid treatment within the previous 6 weeks.
2. Presence of acute infection.
3. Presence of severe oral conditions that may affect saliva collection or measurement.
4. Presence of severe hepatic or renal dysfunction.
5. History of alcohol abuse or psychiatric disorders, including depression.
6. Current treatment with sodium-glucose cotransporter 2 (SGLT2) inhibitors.
Source: ClinicalTrials.gov (NCT07781683). StuddyBuddy aggregates publicly available trial information.
