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Recruiting NCT07780240

Axillary Web Syndrome After Breast Cancer Surgery: Incidence, Risk Factors, and Functional Outcomes

Conditions: Axillary Web Syndrome, Breast Cancer, Breast Cancer Lymphedema, Postoperative Complications

Sex: Female
Ages: 18 Years – 80 Years
Healthy volunteers: No
Enrollment: 250
Sponsor: Antalya City Hospital

Location: Bagcilar Training and Research Hospital Istanbul BAGCILAR

Summary

Axillary web syndrome (AWS), sometimes called "cording," is a condition that can develop after breast cancer surgery in which the lymph nodes under the arm are removed or sampled. It appears as one or more tight, painful cord-like structures running from the armpit down the inner arm. It can limit shoulder movement, cause pain, and interfere with daily activities. It is not yet clear how often AWS occurs, when it typically appears after surgery, which patients are most likely to develop it, or whether it is related to the arm swelling (lymphedema) that some patients experience after breast cancer treatment. Most previous studies looked back at patient records rather than following patients forward in time, so the answers remain uncertain. In this study, women who are having breast cancer surgery with either sentinel lymph node biopsy or axillary lymph node dissection will be examined before their operation and then at set times afterward: 2, 4, and 8 weeks, and 3 and 6 months. At each visit, the study doctor will examine the armpit and arm for cords, measure how far the shoulder can move, ask the patient to rate any pain, and measure the circumference of both arms to check for swelling. The study does not change the surgery or treatment a patient receives. It adds only these examinations and measurements, which are not painful and do not require blood tests or imaging. The researchers hope the results will help identify which patients are at higher risk, so that rehabilitation can be started earlier.

Eligibility Criteria

Inclusion Criteria: * Age 18 years or older * Diagnosis of breast cancer with planned surgical treatment * Axillary staging performed by sentinel lymph node biopsy or axillary lymph node dissection * Written informed consent provided Exclusion Criteria: * Preoperative restriction of shoulder range of motion * History of neuromuscular disease affecting the upper extremity * Metastatic disease * Anticipated inability to comply with the follow-up protocol

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View on ClinicalTrials.gov

Source: ClinicalTrials.gov (NCT07780240). StuddyBuddy aggregates publicly available trial information.