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NCT07776977
Bedtime Device Restriction and Desmopressin in PMNE.
Conditions: Primary Monosymptomatic Nocturnal Enuresis
Sex: All
Ages: 6 Years – 14 Years
Healthy volunteers: No
Phase: NA
Enrollment: 140
Sponsor: Al-Azhar University
Location: Department of Urology, Al-Hussein and Sayed Galal University Hospitals, Al-Azhar University Cairo
Summary
This randomized controlled trial will evaluate whether restricting bedtime digital-device use improves the response to desmopressin in children with primary monosymptomatic nocturnal enuresis. Participants will receive desmopressin for 8 weeks and will be assigned to either bedtime device restriction or usual screen habits.
Eligibility Criteria
Inclusion Criteria:
* Age 6-14 years.
* Diagnosis of PMNE (≥2 wet nights/week for ≥6 months, no daytime symptoms, no prior sustained dryness \>6 months).
* Willingness to take oral desmopressin nightly for 8 weeks.
* Parent/guardian able to monitor and report screen time and wet nights.
* Written informed consent from parent/guardian and assent from child (if age-appropriate).
Exclusion Criteria:
* Secondary enuresis or non-monosymptomatic enuresis (daytime incontinence, urgency, frequency).
* Known organic causes (e.g., diabetes mellitus, urinary tract anomalies, neurological disorders).
* Current use of other enuresis treatments (alarms, anticholinergics, imipramine) within 4 weeks prior to enrollment.
* Severe sleep disorders (e.g., obstructive sleep apnea) or psychiatric conditions affecting compliance.
* Inability to comply with study procedures or follow-up.
Source: ClinicalTrials.gov (NCT07776977). StuddyBuddy aggregates publicly available trial information.