A Clinical Trial of Enlicitide (MK-0616) Formulations in Healthy Participants (MK-0616-044)

Sex: All

Ages: 19 Years – 55 Years

Healthy volunteers: Yes

Phase: PHASE1

Enrollment: 30

Sponsor: Merck Sharp & Dohme LLC

Summary

The goal of this trial is to learn what happens to different formulations (types) of enlicitide in a healthy person's body over time. Researchers will compare the amount of enlicitide in a healthy person's body over time when different formulations are given on an empty stomach and after a high-fat meal.

Eligibility Criteria

Inclusion Criteria: * Is in good health * Has a body-mass index (BMI) between ≥18.0 and ≤32.0 kg/m\^2 Exclusion Criteria: * Has history of gastrointestinal (GI) disease which might affect food and drug absorption or has had gastric bypass or similar surgery. Examples of GI disease include (but are not limited to) recurrent vomiting, inflammatory bowel disease, chronic intestinal disease accompanied by a disturbance in digestion and absorption, Roemheld's syndrome, and severe hernia * Has a history of cancer (malignancy) * Has positive results for human immunodeficiency virus (HIV), hepatitis B surface antigen (HBsAg), or hepatitis C virus (HCV) * Is lactose intolerant

Interested in this study? View the official listing for contact and enrollment details.

View on ClinicalTrials.gov

Source: ClinicalTrials.gov (NCT07776665). StuddyBuddy aggregates publicly available trial information.