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Enrolling By Invitation
NCT07771283
Purpose to Evaluate the Effectiveness of the Superovulation Stimulation Protocol Using Human Chorionic Gonadotropin (hCG) by Demonstrating Its Equivalence to Standard Controlled Ovarian Stimulation Protocols in Terms of Oocytes Retrieved, Blastulation While Maintaining an Economic Advantage
Conditions: Infertility (IVF Patients), Infertility Assisted Reproductive Technology, Infertile Patients, Infertility Drugs, Infertile Women Undergoing IVF or ICSI, Infertility, Stimulation in the Ovary, Infertile Women Undergoing ART, Controlled Ovarian Simulation, Infertile Women Undergoing Assisted Reproductive Technology (ART)
Sex: Female
Ages: 18 Years – 40 Years
Healthy volunteers: No
Phase: NA
Enrollment: 360
Sponsor: LTD "EKODNIPRO", Medical centre Medical Plaza Dnipro
Location: Sali international school of fertility medicine Kampala
Summary
This study evaluates a more affordable medication protocol for ovarian stimulation during in vitro fertilization (IVF). Standard IVF protocols use medications called gonadotropins to stimulate the ovaries to produce multiple eggs, but these medications can be very expensive and create a barrier to treatment. This clinical trial tests whether substituting a significant portion of these standard medications with human chorionic gonadotropin (hCG) is just as effective. Researchers will compare the number and quality of eggs and embryos produced by women using the experimental hCG protocol versus those using the standard gonadotropin protocol. The main goal is to determine if the hCG method can provide similar clinical outcomes and safety profiles while significantly reducing the overall financial cost of IVF treatment.
Eligibility Criteria
Inclusion Criteria:
* Women of reproductive age between 18 and 40 years.
* Clinical indications for the induction of superovulation (undergoing ART/IVF programs).
* Patients with all variants of ovarian reserve.
* Body Mass Index (BMI) up to 35 kg/m².
* Provision of informed consent to participate in the research study.
Exclusion Criteria:
* Presence of ovarian endometriomas.
* History of severe Ovarian Hyperstimulation Syndrome (OHSS) in previous cycles.
* Presence of severe endocrine disorders.
* History or presence of oncological diseases.
* Any medical contraindications to hormonal stimulation.
* Severe male factor infertility (specifically cryptozoospermia)
Source: ClinicalTrials.gov (NCT07771283). StuddyBuddy aggregates publicly available trial information.