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Completed
NCT07768956
Effects of Turkish Coffee and Green Tea in Fatty Liver Disease
Conditions: Non Alcoholic Fatty Liver Disease
Sex: All
Ages: 19 Years – 65 Years
Healthy volunteers: No
Phase: NA
Enrollment: 47
Sponsor: Okan University
Location: Istanbul Dr. Lutfi Kirdar City Hospital Istanbul Istanbul
Summary
Non-alcoholic fatty liver disease (NAFLD) is a common liver condition associated with metabolic disorders and lifestyle factors. This study aims to evaluate the effects of Turkish coffee and green tea consumption in addition to a Mediterranean diet intervention on liver fat content, biochemical parameters, and anthropometric measurements in individuals with fatty liver disease.
Participants received a 12-week Mediterranean diet program and were assigned to groups consuming Turkish coffee, green tea, or no additional beverage intervention. Changes in liver ultrasonography findings, liver enzymes, metabolic parameters, and body measurements were evaluated before and after the intervention.
Eligibility Criteria
Inclusion Criteria:
* Participants aged 19-65 years with a diagnosis of non-alcoholic fatty liver disease (NAFLD).
* Not using medications for diabetes, dyslipidemia, or rheumatoid arthritis.
* Not using dietary supplements.
* No dietary program followed within the previous month.
* No severe psychiatric disorders.
* Willingness to participate in the study and provide informed consent.
Exclusion Criteria:
* Presence of diabetes, dyslipidemia, or rheumatoid arthritis.
* Alcohol consumption.
* Positive hepatitis B surface antigen (HBsAg), hepatitis C positivity, autoimmune hepatitis, liver cirrhosis, toxic hepatitis, or alanine aminotransferase (ALT) levels ≥10 times the upper limit of normal.
* Presence of liver malignancy or hepatic decompensation.
* Use of systemic corticosteroids or methotrexate within the previous 6 months.
* Pregnancy or lactation.
* Regular use of dietary supplements.
* Following a dietary program within the previous month.
* Presence of severe psychiatric disorders.
* High daily consumption of tea and coffee.
Source: ClinicalTrials.gov (NCT07768956). StuddyBuddy aggregates publicly available trial information.