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NCT07767435
Second Trimester Abortion With Letrozole and Misoprostol Compared to Misoprostol Alone
Conditions: Abortion Induced Complicated, Abortion
Sex: Female
Ages: 18 Years – 45 Years
Healthy volunteers: No
Phase: PHASE1, PHASE2
Enrollment: 80
Sponsor: Sohag University
Summary
Termination of Second trimester Abortion with Letrozole and Misoprostol Compared to Misoprostol Alone
Eligibility Criteria
Inclusion Criteria:
* Pregnant women aged 18-45 years.
* Failed pregnancy.
* Gestational age between 14 and 20weeks, confirmed by ultrasonography on the day of admission.
* Hemoglobin concentration \>9 g/dL.
* Closed cervix.
* Absence of products of conception in the cervical canal.
\- Exclusion Criteria:
* Previous attempt to terminate the current pregnancy.
* Molar pregnancy (hydatidiform mole).
* Pathological uterine lesions including uterine fibroids and congenital uterine malformations.
* Cardiac disease.
* Renal disease.
* Hemorrhagic disorders.
* Body mass index (BMI) \>35 kg/m².
* Documented hypersensitivity or allergy to letrozole, misoprostol, or any of the study medications.
Source: ClinicalTrials.gov (NCT07767435). StuddyBuddy aggregates publicly available trial information.
