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NCT07763834
Uromodulin as a Biomarker in Lupus Nephritis
Conditions: Uromodulin, SLE
Sex: All
Ages: 18 Years – N/A
Healthy volunteers: Yes
Enrollment: 90
Sponsor: Assiut University
Summary
Evaluation of Uromodulin as a biomarker of renal histological activity/ Chronicity indices in lupus nephritis
Eligibility Criteria
Inclusion Criteria:
* • Group I: 30 patients with different classes of Lupus Nephritis. These cases are biopsy proven
LN. Histological diagnosis of LN is according to the revised International Society of
Nephrology/ Renal Pathology Society (ISN/RPS) classification and modified National Institute of Health (NIH) activity and chronicity indices (Bajema et al 2018) .
* Biopsy-proven lupus nephritis at the time of uromodulin blood sampling.
* Group II: 10 patients with active SLE without renal involvement and with SLEDAI score ≥6
* Group III: 10 patients with non-active SLE with SLEDAI score \
Source: ClinicalTrials.gov (NCT07763834). StuddyBuddy aggregates publicly available trial information.
