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NCT07753317
Clinical and Radiographic Evaluation of Subgingival 1% Metformin Gel Versus 0.05% Zoledronate Gel as an Adjunct to MINST of Intrabony Defects in Controlled Type 2 DM
Conditions: Controlled Type 2 Diabetic Patients With Periodontitis
Sex: All
Ages: 30 Years – 60 Years
Healthy volunteers: Yes
Phase: NA
Enrollment: 30
Sponsor: Cairo University
Summary
The present randomized placebo-controlled trial aims to evaluate and compare the clinical and radiographic efficacy of subgingivally delivered 0.05% zoledronate gel and 1% metformin gel as adjuncts to minimally invasive nonsurgical treatment of intrabony defects in patients with controlled type 2 diabetes mellitus and periodontitis.
Eligibility Criteria
Inclusion Criteria:
* Diagnosed with type 2 diabetes mellitus, with HbA1c levels \8%) or other systemic diseases that could affect periodontal status.
5. History of radiation therapy to the head and neck
Source: ClinicalTrials.gov (NCT07753317). StuddyBuddy aggregates publicly available trial information.
