Hyaluronic Acid vs I-PRF With Microneedling in Enhancing Peri-implant Soft Tissue

Sex: All

Ages: 21 Years – 50 Years

Healthy volunteers: No

Phase: PHASE2, PHASE3

Enrollment: 42

Sponsor: Ain Shams University

Summary

This study aims to compare the use of microneedling alone versus with hyaluronic acid or i-PRF in conjunction with microneedling in peri-implant mucosa in the esthetic zone to test the superior increase in gingival thickness.

Eligibility Criteria

Inclusion Criteria: * Patients with delayed implants placed in the maxillary esthetic region in correct positioning and angulation * Patients with peri-implant gingival thickness ≤ 1 mm * Patients with healthy gingiva and who can maintain good oral hygiene around implants Exclusion Criteria: * Marginal bone loss ≤ 2 mm * Patients with peri-implantitis or periodontitis * Patients with systemic conditions or diseases impairing healing or soft tissue metabolism * Pregnant or lactating females * Patients taking medications affecting the gingiva

Interested in this study? View the official listing for contact and enrollment details.

View on ClinicalTrials.gov

Source: ClinicalTrials.gov (NCT07750756). StuddyBuddy aggregates publicly available trial information.