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Completed
NCT07749313
Evaluating Elbow Flexion After Free Functional Gracilis Muscle Transfer in Adult Brachial Plexus Lnjury
Conditions: Brachial Plexus Palsy
Sex: All
Ages: 4 Years – 50 Years
Healthy volunteers: No
Phase: NA
Enrollment: 22
Sponsor: Aswan University
Location: Aswan University Hospitals Aswān Aswan Governorate
Summary
* Study Overview This single-arm prospective clinical trial evaluates the efficacy of gracilis free functional muscle transfer (FFMT) for restoring elbow flexion in patients with late-presenting brachial plexus injuries (≥12 months post-injury) or failed prior reconstructive surgery. The gracilis muscle is the preferred donor due to its reliable vascular pedicle, adequate excursion, long motor nerve, and minimal donor-site morbidity .
* Primary Objective To assess postoperative elbow flexion strength using the British Medical Research Council (BMRC) grading system following gracilis FFMT neurotized by intercostal nerves (ICN) or spinal accessory nerve (SAN).
* Secondary Objectives
* Evaluate active range of motion (AROM)
* Measure time to first detectable muscle contraction and time to maximum power
* Assess functional improvement via DASH scores
* Compare outcomes between ICN and SAN neurotization groups
* Compare outcomes between pediatric and adult patients
* Document complications, particularly elbow flexion contracture
* Key Inclusion Criteria
* Age 4-50 years
* Elbow flexion loss or severe weakness for \>12 months following brachial plexus injury (obstetric or traumatic)
* Weak ipsilateral latissimus dorsi and pectoralis major (\
Eligibility Criteria
Inclusion Criteria:
* More than 12 months after injury
Exclusion Criteria:
* younger than 4 years
* older than 50
Source: ClinicalTrials.gov (NCT07749313). StuddyBuddy aggregates publicly available trial information.