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Completed
NCT07749287
Use of Hydrogen Sulphide Donor (N-acetyl Cysteine) in Cases With Acute Ischemic Stroke
Conditions: Ischemic Cerebral Infarction
Sex: All
Ages: 18 Years – N/A
Healthy volunteers: No
Phase: PHASE3
Enrollment: 121
Sponsor: Helwan University
Location: Stroke Unit, Neurology Department, Kasr Al Ainy, Cairo University Hospital Cairo
Summary
1. Clarify novel systemic and local inflammatory mechanisms underlying the cross talk between brain and heart ischemic states,
2. Investigate the new aspects of NAC beyond traditional therapy, in cerebral and myocardial ischemic conditions, both in animal models and clinical cases.
Eligibility Criteria
Inclusion Criteria:
* Age above 18 years
* AIS patients admitted into stroke unit
* Onset within 48 hours
* Glasgow coma scale (GCS) ≥ 8
* Out of window or contraindicated for thrombolytics
* Not arrested before
Exclusion Criteria:
* Age below 18 years
* Cerebral haemorrhage
* Dural sinus thrombosis
* Glasgow coma scale (GCS) \< 8
* Patients received thrombolytic
* Post arrest
Source: ClinicalTrials.gov (NCT07749287). StuddyBuddy aggregates publicly available trial information.
