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Completed
NCT07749027
Comparison Between Low-Dose and High-Dose Nepafenac Sodium
Conditions: Cataract
Sex: All
Ages: 18 Years – 60 Years
Healthy volunteers: No
Phase: NA
Enrollment: 176
Sponsor: Muhammad Aamir Latif
Location: Bahawal Victoria Hospital/Quaid-e-Azam Medical College Bahawalpur Punjab Province
Summary
In South Punjab, Pakistan, where tertiary hospitals manage a high cataract workload, data on nepafenac sodium to reduce this inflammatory response is not up to the mark. Relative benefit of low-dose versus high-dose regimens remains unclear in routine clinical practice. Therefore, this study was performed with the objective to compare the effectiveness of low-dose nepafenac sodium with high-dose nepafenac sodium in preventing macular edema after cataract surgery.
Eligibility Criteria
Inclusion Criteria:
* Any gender
* Aged 18-60 years
* Planned for cataract surgery
Exclusion Criteria:
* Patients with clinical or optical coherence tomography (OCT) evidence of pre-existing macular edema
* Uncontrolled hypertension
* Diabetes mellitus
* Previous stroke
* Renal failure
* Ischemic heart disease with unstable symptoms
* Acute or chronic uveitis
* Retinitis pigmentosa
* Diabetic retinopathy
* Age-related macular degeneration
* Epiretinal membrane
* Retinal vein occlusion
* Glaucoma
* History of intraocular surgery
* Traumatic cataract
* Hypersensitivity to nepafenac or other non-steroidal anti-inflammatory drugs
* Using topical or systemic anti-inflammatory drugs before surgery
Source: ClinicalTrials.gov (NCT07749027). StuddyBuddy aggregates publicly available trial information.
