SleeperOne® 5 Intraosseous Anesthesia in MIH

This randomized split-mouth clinical trial evaluates whether computer-controlled intraosseous anesthesia delivered with the SleeperOne® 5 system reduces pain perception and dental anxiety compared with conventional local anesthesia during restorative treatment of children with molar-incisor hypomineralization (MIH). Thirty-five children received both anesthesia techniques in separate treatment sessions. Pain perception, behavioral responses, dental anxiety, pulse rate, and oxygen saturation were assessed at predefined time points.

Inclusion Criteria: Children aged 8 to 14 years. Bilateral symmetrical MIH-affected permanent first molars requiring restorative treatment. MIH diagnosed according to EAPD criteria. Positive or definitely positive Frankl Behavior Rating Scale. Parent or guardian provided written informed consent. Exclusion Criteria: Acute pulpal or periapical pathology. Developmental dental anomalies other than MIH. Allergy to local anesthetic agents. Medical contraindication to local anesthesia. Analgesic or anti-inflammatory drug use within 24 hours before treatment. Cognitive or communication disorders affecting study assessments. Uncooperative behavior.