Prediction Model of Spontaneous Closure of Congenital Perimembranous Ventricular Septal Defects

The objective of this study is to establish a more comprehensive model for evaluating the condition of children with ventricular septal defect and predicting the probability and time of their spontaneous Closure.

Inclusion Criteria: 1. The initial diagnosis age is from birth to 14 years old 2. Ultrasonography confirmed the presence of simple PMVSD or other simple congenital heart diseases without other complicated heart malformations (such as pulmonary venous drainage, conus trunk malformation, interruption of aortic arch, primary pulmonary hypertension, etc.) 3. No major disease at first diagnosis (life-threatening organic disease not caused by congenital heart disease) 4. The patient or guardian voluntarily signs the informed consent form Exclusion Criteria: 1. The initial diagnosis age\>14 years old. 2. With complicated congenital heart disease (such as pulmonary venous ectopic drainage, conus trunk malformation, interruption of aortic arch, primary pulmonary hypertension, etc.) 3. Serious diseases of other organs 4. Unable to cooperate with the doctor to complete regular outpatient follow-up or give up treatment