Evaluation of Demineralized Dentin Matrix With and Without Injectable Platelet Rich Fibrin as Grafting Materials

Thirty two healthy patients will be selected from the outpatient clinic of the oral and maxillofacial surgery department, faculty of dentistry, Mansoura university, to be included in this study with non restorable teeth in the maxillary esthetic area. After atraumatic teeth extraction, immediate implant placement will be done and buccal jumping gap will be filled by demineralized dentin matrix in study group and control one by demineralized dentin matrix mixed with in injectable platelet rich fibrin.

Inclusion Criteria: * Patient age ranged between 18-40 years old. * Patients seeking to replace non-restorable tooth / teeth in maxillary esthetic zone (anterior \&premolars) by using immediate implant placement. * Cooperative patients with high motivation and good oral hygiene. * Intact socket wall after tooth extraction. * Jumping gap more than 2mm. * Favorable occlusion without presence of parafunctional habits, eg; bruxism and clenching. * Sufficient inter-arch space to accommodate the future prothesis. * Patients able to comply with the required recall visits. Exclusion Criteria: * Patients with known systemic diseases, which can affect normal bone formation or blood coagulation. * Presence of signs of acute infection or pus formation. * Pregnancy. * Smoking. * Patients on bisphosphonate drug.