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Completed
NCT07723183
Soft and Hard Tissue Healing Following Alveolar Ridge Preservation of Mandibular Third Molar Extraction Socket Filled With Auto Tooth Bone Graft or Alloplastic Graft
Conditions: Wisdom Tooth, Socket Preservation
Sex: All
Ages: 18 Years – 35 Years
Healthy volunteers: Yes
Phase: PHASE4
Enrollment: 12
Sponsor: University of Malaya
Location: Faculty of Dentistry Universiti Malaya Kuala Lumpur Wilayah Perseketuan Kuala Lumpur
Summary
This study compared two bone graft materials: 1. Auto Tooth Bone (ATB) (made from the patient's own extracted tooth) and 2. EthOss® a synthetic alternative. This is to see how well they prevent bone and gum damage after lower wisdom tooth removal. In this split-mouth trial, participants had both lower wisdom teeth removed, with one socket receiving ATB and the other receiving EthOss®. Over a 24-week follow-up period, researchers tracked patient clinically on their comfort, gum healing, and new bone growth using X-rays. The study found that both materials performed similarly and showing no significant differences in pain, swelling, complications, or gum healing. While there was a statistical difference in final bone depth. Both grafts successfully stimulated new bone growth, proving that ATB and EthOss® are equally safe, reliable, and effective options for supporting recovery after wisdom tooth surgery.
Eligibility Criteria
Inclusion Criteria:
* Patient who requires surgical removal of bilateral impacted M3.
* Patient with impacted bilateral M3 which are sound.
* Impacted bilateral M3 classified as Class I or II with Level A or B according to Pell and Gregory's classification.
* Presence of M2 adjacent to the M3 to be extracted.
* Patient aged 18 to 35 years old.
* Patient with periodontal status of:
* Basic Periodontal Score (BPE) 2 at lower right and lower left sextants.
* Full mouth plaque score \
Source: ClinicalTrials.gov (NCT07723183). StuddyBuddy aggregates publicly available trial information.